Variously referred to as Nicotinamide Riboside (NR), Niagen is a patented formula that is not only the first, but the only commercially available form of Nicotinamide Riboside.
It is a highly effective NAD+ (nicotinamide adenine dinucleotide) precursor to mitochondrial health that also functions as a niacin (vitamin B3) supplement.
This means that it mitigates the effects of aging throughout the mind and body as well as boosts cellular energy.
This, perhaps, explains why Niagen and Nicotinamide Riboside are often touted as a fountain of youth since they are linked with numerous health benefits including improved cardiovascular health, better endurance, anti-aging support, and cognitive enhancement.
What is Niagen and Nicotinamide Riboside – What’s the difference?
Nicotinamide Riboside and Niagen are not exactly the same with the latter being a patented formula produced by ChromaDex (an American pharmaceutical company).
ChromaDex manufactures NR in a raw form and under the Niagen trademark. However, other pharmaceutical companies can still purchase this raw material from ChromaDex and sell it as their own supplements and formulas- with some of these companies adding preservatives or fillers to the formula while others leave it as-is.
The result is various types of Niagen supplements from different pharmaceutical companies, with one of the most popular being that manufactured by Live Cell Research. Essentially, however, Niagen is just Nicotinamide Riboside that is marketed using a catchy brand name.
Niagen is a nutritional supplement that was discovered as recently as late 2013 by Dr. David Sinclair of Harvard Medical School whilst performing clinical research on mice.
That research showed that when mice were given Nicotinamide Riboside molecules, their cell age decreased from 2 years to about 6 months. Therefore, not only does Niagen mitigate the effects of aging, it appears to turn back the clock and make cells function in a manner similar to how they did when younger. This is the closest that science has ever come to reversing the effects of aging.
Of course you’ll still need to exercise and eat properly if you want to get six pack abs after 40, but Niagen may give you the youthful boost you need to complete prescribed workout plans in any fitness program.
Niagen functions by increasing the NAD+ chemical in the cells. Raising the levels of this chemical in the cells reduces aging within them thereby elevating your mood and providing you with better energy. It is also thought to enhance mental clarity, improve metabolism, and reduce the risk of Alzheimer’s, cancer, and heart disease.
The only downside to Niagen so far is that it has not been subjected to independent research or rigorous clinical trials- having only been discovered less than 2 years ago. But research done thus far confirms its beneficial health effects, with few side effects reported.
The case for Niagen
Dr. David Sinclair of Harvard Medical School is widely acknowledged for having identified the chemical referred to as NAD which has been proven to reverse the effects of aging in living cells.
In fact, he has been successful in extending the lifespan of yeast by at least 30%. With regards to Niagen, Dr. Sinclair injected mice that were about 2 years old with an NR molecule that had been converted to NAD+. And just a week down the line the cells of the mice had reverted to the cells of mice that were the equivalent of 6 months old.
That is the same as turning the cells of a 65-year old into the cells of a 30-year old on a human scale. Here are 3 reasons why Niagen is currently considered a big deal in the medical fraternity:
- Prevents tumor formation and DNA damage
- Prevention of noise related hearing loss
- Reverse skeletal muscle aging
Some of the most exciting Nicotinamide Riboside research centers on measuring the effects of NR on cancers, tumors, and other deadly diseases. A November 2014 study on mice showed that the restoration of NAD+ pools with Nicotinamide Riboside (NR) could prevent tumor formation and DNA damage. And even though early results are promising, it still remains unknown whether these effects will carry over to humans.
The effects of NR on hearing loss were also conducted towards the close of last year with researchers establishing that the administration of NR following noise exposure prevented noise-induced hearing loss.
Studies in the last year also proved that restoring NAD+ levels not only provided anti-aging effects, but had positive overall effects as well. These effects included reversing the effects of aging on organs like the heart and a partial reversal of skeletal muscle aging.
Niagen has been successful on yeast and mice. However, the first human clinical study was launched in July 2014 and the medical world still awaits the results of that study.
Choosing the right Niagen supplement
As mentioned earlier, ChromaDex licenses its trademark formula to various companies who then put their unique spin on the Niagen formula. Some companies, however, buy the formula and leave it untouched. Currently, the most popular Niagen supplement is, arguably, that which is offered by Live Cell Research which claims to sell 250mg of 100% Niagen.
Similar to Bio X4 by Nucific, Niagen is manufactured with the highest quality ingredients and does not use binders or fillers. As a result, and due to the low toxicity of Nicotinamide Riboside, Niagen is relatively safe and devoid of side effects.
Where to buy Niagen and how much is it?
Niagen is currently offered by Live Cell Research in 3 different options i.e. one bottle that costs about $47, two that cost $83, and three costing $117.
And as with many things in life, the more bottles you buy, the more you save.
Shipping is also free if you purchase more than one bottle although a standard shipping rate of $4 applies when you buy one bottle.
Live Cell Research also offers a 90 day money back guarantee where you can return the product within the stipulated period with no questions asked.
The bottom line on our Niagen review
As one of the hottest and newest supplements on the market, Niagen appears to offer some powerful anti-aging benefits across your mind and body.
The early clinical evidence is convincing and continues to mount- that Nicotinamide Riboside and Niagen have been shown to reverse aging by targeting anti-aging compounds within the cells. The only catch is that scientists have yet to publish the results of the human trials conducted mid last year.
You can still buy it, try it, and if unimpressed, return it for a full refund within the set period of 90 days. Such a flexible return policy goes to show how companies such as Live Research are confident about their newest pharmaceutical supplement.